Welcome to the TACIT website

TACIT stands for Tool for Addressing Conflicts of Interest in Trials and is a tool that provides review authors with a framework for addressing conflicts of interest in trials included in Cochrane Reviews and other systematic reviews.

We aim to develop a tool that facilitates a systematic and transparent judgement of "notable concern" about conflicts of interest in relation to funders and researchers involved in randomised clinical trials included in Cochrane reviews and other systematic reviews.

In addition, TACIT also address the sufficiency of information that the conflicts of interest assessment was based on. These assessments can then be used in exploratory meta-analyses to examine whether results in trials with notable concern differ from those of trials with no notable concern.